IMPROVED MILBOND-TX® “SAFETY STUDY WITH EGG-TYPE LAYING HENS”
In experiments specifically designed to establish the safety of Improved Milbond-TX® (IMTX) in broiler diets containing higher than the recommended dietary concentration of 0.25% (2.5 g/kg diet), researchers (Miles and Henry, 2007a: Ledoux et al., 1999) reported no detrimental effects on broiler performance. Their findings, from feeding up to 2.0% IMTX in broiler diets, were presented in summarized form in two of the past issues of “MILWHITE’S INFORMATION PAGE”. Following this research on safety of IMTX in broiler diets an experiment was designed to establish the safety of IMTX fed at up to 2.0% in commercial egg-type laying hen diets. The study was conducted at the University of Florida using Hy-Line W-36 hens fed a typical corn-soybean meal based diet. The following is a brief summary of this safety study.
Researchers conducting this study (Miles and Henry, 2007b) decided not only to establish the safety of IMTX in laying hen diets, but to design the study to determine if feeding high dietary concentrations of IMTX affected hens known to be laying eggs with high shell weight or low shell weight. Prior to feeding high dietary concentrations of IMTX to hens the researches (Miles and Henry, 2007b) separated the hens into two groups according to their shell weight. Three eggs were collected from each of 300 individually caged, thirty-five-week old hens. The eggs were weighed, broken out, washed of excess albumen and dried to determine the average shell weight for each individual hen. All hens were ranked by shell weight based on mean shell weight of the 3 eggs collected. The 75 hens with the highest and 75 hens with the lowest shell weights were allocated randomly to 5 replicate pens of 5 individually caged birds with either high or low shell weight for the experiment. Each pen of 5 hens was assigned randomly to 1 of 3 dietary treatments, which were the corn-soybean meal basal diets supplemented with 0, 1.0 or 2.0% IMTX. Feed and water were offered ad-libitum to the hens throughout the 5 28-day experimental periods. Data on bird performance and egg characteristics were collected at pre-determined days during each 28-day experimental period. Also, during the fourth 28-day period, excreta were collected from all replicate pens of five hens for moisture determination.
When the data were collected and analyzed for this study, IMTX fed at concentrations higher than the recommended amount in the diet proved to be safe and did not affect any component of laying hen performance. Hen mortality was less than 3% during the entire experimental period and was not related to any dietary treatment. Feed intake, Feed conversion, and hen-day egg production in both groups of hens selected for their eggshell weight was not influenced by the addition of IMTX to the diet. Change in hen body weight during the five-month experimental period did not differ among treatments for hens in the shell weight groups, nor was there an effect due to IMTX. Egg characteristics (egg weight, shell weight and Haugh units (albumen quality) were not affected by IMTX during the entire 20 week experimental period. Values for excreta moisture of hens in the shell weight groups were similar and IMTX did not have any influence on excreta moisture.
The data collected in this experiment with commercial egg-type laying hens, supports the conclusion obtained with broilers, that feeding higher than recommended amounts of IMTX in the diet is safe. No detrimental effects on laying hen performance or egg characteristics resulted from feeding up to 2.0% IMTX in the diet continuously for 5 months to commercial egg-type laying hens grouped according to their ability to lay eggs with high or low egg shell weight.
Note: A complete description of this experiment with egg-type laying hens which was conducted at the University of Florida and the data collected in the experiment can be found in the referenced publication (Miles and Henry, 2007b) located in the footnote below. The information presented in this issue of MILWHITE’S INFORMATION PAGE was compiled by Dr. Orlando Osuna, Director of Health Science at Milwhite, Inc. and Dr. Richard Miles, Professor Emeritus, University of Florida, Gainesville, FL, USA.
Miles, R.D. and P.R. Henry. 2007a. Safety of Improved Milbond-TX® when fed in broiler diets at greater than recommend levels. Animal Feed Science and Technology. 138:309-317.
Miles, R.D. and P.R. Henry. 2007b. Safety of Improved Milbond-TX® when fed to laying hens at higher-than-recommended levels. Journal of Applied Poultry Research. 16:404-411.
Ledoux, D.R., G.E. Rottinghaus, A.J. Bermudez and M. Alonso-Debolt. 1999. Efficacy of a hydrated sodium calcium aluminosilicate to ameliorate the toxic effects of aflatoxin in broiler chicks. Poultry Science. 78:204-210.