The success of Improved Milbond-TX® in reducing AFM1 contentration of milk of dairy cows was published by the Department of Animal Science, North Carolina State University in Raleigh and Texas A&M University in College Station, TX (J.S. Stroud, E.A. English, S. Davidson, B.A. Hopkins, W.M. Hagler, Jr., C. Brownie, G. Latimer and L.W. Whitlow, 2006).
Table 1. Percent reduction in milk aflatoxin concentration, milk aflatoxin secretion and
milk aflatoxin transfer due to addition of adsorbent products at 0.5% diet DM
||Milk Aflatoxin Concentration
||Milk Aflatoxin Secretion
||Aflatoxin Transfer from feed to milk
|Product A (yeast and silicates)
|Product B (yeast and silicates)
|Product C (silicates)
|Product D (silicates)
|Product E (yeast and silicates)
|Product F (silicates)
|Product G (silicates)
|Pooled Standard Error
Table 1: *Values are different from zero when P<0.05 and products that significantly reduced milk aflatoxin concentration, secretion and transfer from feed to milk. Reference: (J.S. Stroud, E.A. English, S. Davidson, B.A. Hopkins, W.M. Hagler, Jr., C. Brownie, G. Latimer and L.W. Whitlow: The Effect of Feed Additives on Aflatoxin in Milk of Dairy cows fed with Aflatoxin Contaminated Diets. Master of Science tests. Dept. of Animal Sciences, N.C. State University 2006).
When IMTX was added at 1% to mycotoxin-free diets, there was no sign of nutritional deficiency or negative effect on dietary nutrients (minerals, vitamins, etc.) at this dietary level (Ledoux et al., Poultry Science 78.204-210, 1999). Proven to be safe up to 2% inclusion rate (8 times recommended dosage). References: (Miles, R.D. and Henry, P.R.: Safety of Improved Milbond-TX When Fed to Laying Hens at Higher-Than-Recommended Levels. J. Appl. Poult. Res. 16:404-411. 2007). (Miles, R.D. and Henry, P.R.: Safety of Improved Milbond-TX When Fed in Broiler Diets at Greater Than Recommended Levels. Animal Feed Science and Technology 138:309-317, 2007).
IMTX does not complex dietary phosphorus and therefore does not prevent adsorption and utilization of P for bone formation which was demonstrated by toe ash and serum P in the experimental animals. (Miles, R.D. and Henry, P.R.: Safety of Improved Milbond-TX When Fed in Broiler Diets Limiting in Available Phosphorus or Containing Variable Levels of Metabolizable Energy. J. Appl. Poult. Res. 16:412-419, 2007).